ECE-690-501: Genomic Signal Processing (Winter, 2008)
CRN |
23890 |
Course Number |
ECE-S690 |
Section Number |
501 |
Credits |
3.0 |
Time |
Wednesdays 6pm - 8:50pm |
Office Hours |
upon request (email me) |
Room |
Bossone 616 |
Instructor |
Gail Rosen |
Restrictions |
signals and systems |
Department |
Electrical and Computer Engineering |
Description
This course focuses on signal processing(SP) applied to analysis and design
of biological systems. This is a growing area of interest with many topics
ranging DNA sequence analysis, to gene prediction, sequence alignment, and
bio-inspired SP for robust system design.
References (put on reserve at the library)
- Biological sequence analysis, Durbin et al., 8th edition, 1998.
- Introduction to Genomic Signal Processing with Control, Dhatta and Dougherty, 2006.
Grading
Homework Assignments | 30%
|
Literature Review / Final Project Proposal (Due Feb. 6))
| 30% |
Progress Report (Due Feb. 27) |
10% |
Final Project (Due March 19) | 30%
|
Proposed Timeline (subject to change)
Week 1 | Introduction, Tools, and Databases
|
Week 2 | Introduction to Molecular Biology |
Week 3 | DNA Representation, Analysis, and Bioinformatics Tools
|
Week 4 | Pairwise Alignment,
BLAST, Phylogeny |
Week 5 | Introduction to HMMs |
Week 6 |
Literature Review and Project Proposals |
Week 7 |
HMMs for Gene and CpG island prediction |
Week 8 |
Information Theory and Pattern Finding in DNA |
Week 9 | AR Modeling and Compression of DNA sequences |
Week 10 | Modeling Genetic Pathways |
Week 11 | Final Projects |
Disability Information
Student with disabilities requesting accommodations and services at
Drexel University need to present a current accommodation verification
letter (AVL) to faculty before accommodations can be made. AVL's are
issued by the Office of Disability Services (ODS). For additional
information, contact ODS at www.drexel.edu/edt/disability, 3201 Arch
St., Street, Suite 210, Philadelphia, PA 19104, 215.895.1401 (V), or
215.895.2299 (TTY).