ECE-690-501: Genomic Signal Processing (Winter, 2008)


CRN 23890
Course Number ECE-S690
Section Number 501
Credits 3.0
Time Wednesdays 6pm - 8:50pm
Office Hours upon request (email me)
Room Bossone 616
Instructor Gail Rosen
Restrictions signals and systems
Department Electrical and Computer Engineering

Description

This course focuses on signal processing(SP) applied to analysis and design of biological systems. This is a growing area of interest with many topics ranging DNA sequence analysis, to gene prediction, sequence alignment, and bio-inspired SP for robust system design.

References (put on reserve at the library)

  • Biological sequence analysis, Durbin et al., 8th edition, 1998.
  • Introduction to Genomic Signal Processing with Control, Dhatta and Dougherty, 2006.

Grading

Homework Assignments30%
Literature Review / Final Project Proposal (Due Feb. 6)) 30%
Progress Report (Due Feb. 27) 10%
Final Project (Due March 19)30%

Proposed Timeline (subject to change)

Week 1Introduction, Tools, and Databases
Week 2Introduction to Molecular Biology
Week 3 DNA Representation, Analysis, and Bioinformatics Tools
Week 4 Pairwise Alignment, BLAST, Phylogeny
Week 5 Introduction to HMMs
Week 6 Literature Review and Project Proposals
Week 7 HMMs for Gene and CpG island prediction
Week 8 Information Theory and Pattern Finding in DNA
Week 9 AR Modeling and Compression of DNA sequences
Week 10 Modeling Genetic Pathways
Week 11 Final Projects

Disability Information

Student with disabilities requesting accommodations and services at Drexel University need to present a current accommodation verification letter (AVL) to faculty before accommodations can be made. AVL's are issued by the Office of Disability Services (ODS). For additional information, contact ODS at www.drexel.edu/edt/disability, 3201 Arch St., Street, Suite 210, Philadelphia, PA 19104, 215.895.1401 (V), or 215.895.2299 (TTY).